Division of Physiology, GKT School of Biomedical Sciences and *Thrombosis & Vascular
Is mild Normobaric Hypoxia a risk factor for deep vein thrombosis?
PD Hodkinson, BJ Hunt*, K Parmar* & J
Ernsting*
Modern air travel entails a cabin altitude between 1520-2440m (5000-8000ft) and thus exposure to mild hypoxia. There is debate as to whether hypoxia is causally related to deep vein thrombosis (DVT) occurring during or after travel. One study suggested that a short period of hypobaric hypoxia causes activation of coagulation.
The aim of this study was to test the hypothesis that hypoxia alone (normobaric hypoxia) causes activation of coagulation, possibly through endothelial cell activation.
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